User blog comment:Xilinoc/Ch. 608 - whatever the title of this one is/@comment-1268838-20141204141532/@comment-1351982-20141204202352

I can't see Uryū going that dark and it would be extremely out of character and out of no where. Uryū has been a main supporting character for the majority of the series and there simply isn't enough build up for him to be the big bad. This is a bad example, but despite the quality of the writing, Anakin Skywalker had build up to his eventually transition into Darth Vader. Uryū does not have this. Plus Ichigo would not want to kill his friend, especially since we know they're related. I don't want to go too much into speculation, but short of giving a guarantee, I extremely doubt Uryū will willingly become the final antagonist.