User blog comment:Xilinoc/Ch. 583 - The Headless Star 2/@comment-1969544-20140604075303/@comment-5398287-20140604204634

To my knowledge, it's the ONLY time he's ever fought a female character before. He tried to attack Loly and Menoly once when they were hurting Orihime, but Ulquiorra was all like "nope."