User blog comment:Mohrpheus/Spiritual Imbalance in Bleach - The End of the World?!/@comment-2175469-20100901204444/@comment-1268838-20100901205134

Considering that the Hollows literally rip these Pluses apart before eating them (with blood, gore, and all), I find it hard to believe that they would simply recover. Like I said above, Ichigo acknowledged that his mother could never pass on to the afterlife because Grand Fisher ate her soul. The way I see it, once the soul is broken down into energy for the Hollow, there's no way to change it back. As far as the fused souls go, that has only been confirmed for Hollows, because the initial components of the Gillian fuse together rather than simply eat each other.