User blog comment:Lia Schiffer/390: Beyond The Death Understanding/@comment-44061-20100129204237

Aside for Yoruichi whose a hand-to-hand combatant who in not certain we can assume she could take him, we dont know the level of Isshin's power so thats not definite and im not sure how Ryuken can even place he is a human qunicy, probably better then his son but Thats giving him way to much credit when its highly unlikely.